Resistance to Ibritumomab in Lymphoma by Makoto Hosono & Jean-François Chatal

Author:Makoto Hosono & Jean-François Chatal
Language: eng
Format: epub
Publisher: Springer International Publishing, Cham

5 Conclusions

In conclusion, FDG-PET/CT is a useful noninvasive imaging modality for monitoring the response of NHL to RIT. In our experience, negative PET findings before and at 3 months after RIT predict the treatment effects with high probability. However, positive PET results at 3 months after RIT do not warrant immediate additional therapy because metabolic response to RIT can be gradual, with continued declines of FDG uptake occurring between 7 and 9 months after RIT without additional therapy. The optimal condition of imaging, especially the time interval between the therapy and the FDG-PET/CT scan, is to be established by further prospective studies with a large number of patients.

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